Genotyping and Breast Cancer...!

Genotyping and Breast Cancer

Breast cancer is a cancer of the glandular breast tissue. In India an average of 80,000 women are diagnosed with carcinoma of the breast, and 40,000 women die of this disease every year and it is the second most common cancer among Indian women (19%) after cervical cancer (30%).

How genetics is useful for Breast Cancer Identification?

1. Carrier Status:

Five to 10 percent of breast cancers occur in women with a genetic predisposition for the disease, usually due to mutations in either the BRCA1 or BRCA2 genes.

2. Health Risks:

After BRCA mutations, the riskier version of this SNP, also known as the CHEK2 1100delC mutation, is one of the more common known genetic variants associated with breast cancer.


Comparative study of the standard and the Patient’s genotype shows the presence of mutated gene in the Patient’s DNA which would be useful in treatment for the specific cancer.

Next Post »